Reproduction of the Antitumor Effect of Cisplatin and Cetuximab Using a Three-dimensional Spheroid Model in Oral Cancer.

Int J Med Sci · 2022 · PMC9346383 · PMID 35928727

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Interestingly, SAS showed a trend of attenuated EGFR expression in 3D culture compared to 2D culture, while conversely, HSC-3 showed a trend of enhanced EGFR expression in 3D culture compared to 2D culture (Fig. 1 F,G).

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