As the current study demonstrates limitation of the DAR indices as a biomarker for studying atrophic encephalopathy but also a significant trend of beta activities yielding in cases of brain atrophy, a focused Beta-alpha ratio biomarker was designed to target the occipital electrodes (O1 and O2), which are known to be the reference points for studying background activities of the brain 52 .
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The focused quantitative EEG bio-marker in studying childhood atrophic encephalopathy.
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Further analysis shows insignificance also when gender variation is considered, although a slight trend of significance leans more towards male children (data not shown).
Regarding age, the current study finds an increasing trend of neuroimaging with control subjects in which the peak incidence was noted at the age of above 15 involving children who were not cases of brain atrophy.