Analysis of archaic human haplotypes suggests that 5hmC acts as an epigenetic guide for NCO recombination.

Although direct correlations with the entire data set were weak (rho values of the Spearman’s rank correlation were only 0.07 for GWAVA and 0.01 for fitCons scores), a correlation with the average scores of NCO rate bins revealed a significant trend for GWAVA-scores and no association with fitCons scores (Fig. 2 a).

also in 9,775 other papers