Pregnancy, parity and risk of RA In an initial small case-control study, pregnancy was associated with a reduced risk of RA onset which did not reach statistical significance [odds ratio (OR) 0.3, 95% CI 0.04–2.6], while there was an increased incidence of RA during the first 3 months post-partum (OR 5.6, 95% CI 1.8–17.6) ( 66 ).
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What is the impact of sex hormones on the pathogenesis of rheumatoid arthritis?
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