Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition.

The negative relationship between proportion of activated (CD38/HLA-DR) CD8 + T cells and CD4 counts did not reach statistical significance ( Figure 7E ), but proportion of activated (CD38/HLA-DR) CD8 + T cells were positively correlated with HIV plasma viral loads among viremic PLWH (r=0.8, p=0.0006; Figure 7F ).

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