Biomarker Changes and Molecular Signatures Associated with Takayasu Arteritis Following Treatment with Glucocorticoids and Tofacitinib.

14 , 25 In the current study, higher baseline levels and a decreasing trend post treatment of IL-6 were seen in TAK patients, which was similar to PTX3.

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After treatment with GCs and TOF, MMP9 showed a trend of increasing first and then decreasing; interestingly, the trend of MMP3 levels was the opposite.

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The radar plot indicates that the levels of PTX3 presented an increasing trend as the increase in NIH scores at baseline ( Figure 3A ).

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