Barely Significant
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The yin-yang effects of immunity: From monoclonal gammopathy of undetermined significance to multiple myeloma.

Front Immunol · 2022 · PMC9357873 · PMID 35958625

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an elevated trendno p-value reported
Conversely, the expression of CD86 and CD83 showed an elevated trend.

also in 278 other papers

a marked trendno p-value reported
There was a marked trend towards lower expression of HLA-DR and HLA-A, B, and C on mDCs and pDCs of MM patients compared to HDs ( 41 ).

also in 422 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.