Antibody affinity and cross-variant neutralization of SARS-CoV-2 Omicron BA.1, BA.2 and BA.3 following third mRNA vaccination.

Nat Commun · 2022 · PMC9358642 · PMID 35941152

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did not reach statistical significanceno p-value reported

The antibody binding affinity against WA1 in the hybrid immunity group trended higher than the naïve group at one month after the 2nd vaccine dose (1.6-fold), one month after the 3rd dose (2.5-fold) and four months after the 3rd dose (2.1-fold) but these differences did not reach statistical significance (Fig. 2b ).

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