Molecular Changes In Cardiac Tissue As A New Marker To Predict Cardiac Dysfunction Induced By Radiotherapy.

In contrast, a decreasing trend was found exclusively for the highest daily dose ( Figure 6D , left panel).

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Interestingly, later, at 12 months, an increasing trend was found for circulating cTnT in response to the daily doses of 0.3 and 1.2 Gy administered for 23 days ( Figure 6D , right panel), suggesting that at this time point the highest cumulative doses promote subclinical cardiac dysfunction, corroborated by GLS impairment detection ( Figure 2 ).

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Moreover, the expression level of Il6 showed a trend of augmentation, exclusively in response to the daily dose of 1.2 Gy.

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