Imaging Glioblastoma Metabolism by Using Hyperpolarized [1-<sup>13</sup>C]Pyruvate Demonstrates Heterogeneity in Lactate Labeling: A Proof of Principle Study.

Metabolism of the NABP The pyruvate and lactate signal intensities were higher in the ipsilateral NABP than in the NABP in the contralateral non–tumor-bearing hemisphere, although this did not reach statistical significance ( n = 7, P = .26 and P = .24).

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