18 Although the increase in the plasma concentrations of S1 and HSPG after FLT in our study did not reach statistical significance, Johansson et al. 19 demonstrated that S1 is a valid marker of EG degradation, and its increment in plasma in patients with septic shock is associated with severe systemic inflammation, coagulopathy, and high mortality.
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The Glycocalyx Shedding Influences Hemodynamic and Metabolic Response to Fluid Load in Septic Shock.
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