Involvement of B cells in the development of systemic sclerosis.

Front Immunol · 2022 · PMC9365989 · PMID 35967355

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a decreasing trendno p-value reported

In the placebo group, the %FVC and %DLco values showed a decreasing trend but no significant worsening over the course of 1 year.

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showed a trendno p-value reported

This trial had a high proportion of patients with mild SSc-associated interstitial lung disease, but a subanalysis of only patients with baseline %FVC less than 80% also showed a trend toward better %FVC in the rituximab group than in the placebo group.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.