The Effects of Nutrient Signaling Regulators in Combination with Phytocannabinoids on the Senescence-Associated Phenotype in Human Dermal Fibroblasts.

Simultaneously, the highest cell viability after the five-day exposure in the senescent fibroblasts was achieved with 50 μM of TRSV ( Figure S1H ), while metformin showed a trend to increase cell viability ( Figure S1D ) and rapamycin-treated fibroblasts demonstrated no change at all ( Figure S1L ).

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