Associations of HLA genetic variants with carbamazepine-induced cutaneous adverse drug reactions: An updated meta-analysis.

Clin Transl Sci · 2022 · PMC9372413 · PMID 35599240

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did not reach statistical significanceno p-value reported

Previous meta‐analyses found HLA‐A*24:02 , HLA‐B*40:01 , HLA‐B*46:01 , and HLA‐B*58:01 as strong protective biomarkers; however, the present analysis found a trend towards reduction of risk but did not reach statistical significance, suggesting conducting more research is needed to establish such associations.

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