Barely Significant
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Effects of lidocaine and esmolol on hemodynamic response to tracheal intubation: a randomized clinical trial.

Braz J Anesthesiol · 2022 · PMC9373404 · PMID 34582903

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Although the esmolol group demonstrated an AUC lower than the overall heart rate, this variable did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.