There were also apparent increases in LPP2 mRNA in ER positive (3.0-fold), HER2 positive (6.0-fold), and ER/PR/HER2 positive (3.8-fold) breast cancer compared to normal breast tissue, although these did not reach statistical significance (Figure 1 A).
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Lipid phosphate phosphatase-2 promotes tumor growth through increased c-Myc expression.
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