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Guideline Adherence As An Indicator of the Extent of Antithrombotic Overuse and Underuse: A Systematic Review.

Glob Heart · 2022 · PMC9374022 · PMID 36051325

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a clear trendno p-value reported
While a previous review reported increasing overuse of multiple practices over the years [ 58 ], the estimates in our study did not indicate a clear trend in guideline adherence improvement or worsening overtime, but we did not formally examine this.

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