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Polymorphism AGT2 (rs4762) is involved in the development of dermatologic events: Proof-of-concept in hepatocellular carcinoma patients treated with sorafenib.

World J Hepatol · 2022 · PMC9376774 · PMID 36158918

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closest p · 1.2× alpha
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boldest claim

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showed a trendP value = 0.06so close (0.05 < p ≤ 0.1)
By contrast, the AGT2 (rs4762) AA genotype was associated with a significant increased risk of eDAE with a HR = 4.43 (95%CI: 1.01-19.39; P value = 0.048; AA vs GG) in the univariate analysis, and showed a trend in the multivariate model with a HR = 4.24 (95%CI: 0.95-19.06]; P value = 0.06; AA vs GG), Table 5 .

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