showed a trendP value = 0.06
By contrast, the AGT2 (rs4762) AA genotype was associated with a significant increased risk of eDAE with a HR = 4.43 (95%CI: 1.01-19.39; P value = 0.048; AA vs GG) in the univariate analysis, and showed a trend in the multivariate model with a HR = 4.24 (95%CI: 0.95-19.06]; P value = 0.06; AA vs GG), Table 5 .