Inflammatory stimuli alter bone marrow composition and compromise bone health in the malnourished host.

Front Immunol · 2022 · PMC9380851 · PMID 35983045

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Expression of genes involved in osteogenesis, such as Dentin matrix acidic phosphoprotein 1 (Dmp1), Runt-related transcription factor 2 (Runx2), Osteocalcin (Bglap), and Osterix (Osx), showed a trend toward a decrease in LPS-challenged MN mice compared with naïve MN mice, but this difference was not observed in well-nourished mice ( Supplementary Figures 3A, B ).

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