De novo variants in genes regulating stress granule assembly associate with neurodevelopmental disorders.

Sci Adv · 2022 · PMC9385150 · PMID 35977029

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nominally significantno p-value reported

On the basis of data from 40,853 individuals with NDDs, we report a nominally significant excess of de novo variants within 29 genes that are not implicated in NDDs, including 3 essential genes ( G3BP1 , G3BP2 , and UBAP2L ) in the core SG interaction network.

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