High expression of Sterol-O-Acyl transferase 1 (SOAT1), an enzyme involved in cholesterol metabolism, is associated with earlier biochemical recurrence in high risk prostate cancer.

Prostate Cancer Prostatic Dis · 2022 · PMC9385470 · PMID 34326474

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2B ) showed a trend for shorter BCR with a median of 91 months (95% CI not computed) compared to 125 (111.5–158.5 months) in patients with low SOAT2 staining ( n = 247, Log rank p = 0.05).

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