The aberrant activation of the TLR-4/NF-κB/NLRP3 is quite significant in the formation and maintenance of the inflammatory microenvironment during hepatic IRI 35 .
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Salidroside alleviates hepatic ischemia-reperfusion injury during liver transplant in rat through regulating TLR-4/NF-κB/NLRP3 inflammatory pathway.
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