CaMKII is a modulator in neurodegenerative diseases and mediates the effect of androgen on synaptic protein PSD95.

Front Genet · 2022 · PMC9386121 · PMID 35991539

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quite significantno p-value reported

The effects of testosterone as a pharmacological agent acting on neuronal cells and calcium as a messenger ion are quite significant, and they may hold the potential for treat degenerative diseases.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.