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C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimer's disease.

Acta Neuropathol Commun · 2022 · PMC9386996 · PMID 35978440

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showed a trendno p-value reported
Additionally, in both regions analyzed, PMX205 showed a trend towards a decrease of the total number of Iba1 + cells in AD mice.

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