Patients on VDZ showed a higher rate of clinical worsening since the introduction of the biologic agent compared with non-gut selective therapies, even if the results did not reach statistical significance (15.5 vs. 7.3%, 7/45 vs. 13/179, p = 0.08).
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The impact of biologic therapies on extra-intestinal manifestations in inflammatory bowel disease: A multicenter study.
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