Behavioural and molecular characterisation of the Dlg2 haploinsufficiency rat model of genetic risk for psychiatric disorder.

Genes Brain Behav · 2022 · PMC9393932 · PMID 35075790

Europe PMC DOI

hedged sentence

0.0860

closest p · 1.7× alpha

0.0860

boldest claim

The sentences

approached significancep = 0.086so close (0.05 < p ≤ 0.1)

There was no main effect of genotype ( F (1, 49) = 0.452, p = 0.505, n 2 p = 0.009; BF exclusion = 2.165) but the time bin × genotype interaction approached significance ( F (2, 98) = 2.516, p = 0.086, n 2 p = 0.049; BF exclusion = 1.243) with Dlg2 +/− rats showing a slight tendency to a faster reduction in activity across the 30 min pre‐injection habituation period.

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