Clonal heterogeneity and rates of specific chromosome gains are risk predictors in childhood high-hyperdiploid B-cell acute lymphoblastic leukemia.

Mol Oncol · 2022 · PMC9394234 · PMID 35726693

Europe PMC DOI

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0.0640

closest p · 1.3× alpha

0.0640

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The sentences

showed a trendP = 0.064so close (0.05 < p ≤ 0.1)

Analysis of clonal heterogeneity in matched DX‐REL samples showed a trend towards reduced entropy levels in REL samples ( P = 0.064), with six of 10 patients showing lower entropy levels in the REL samples (Fig. 6D ), supporting previous data on DX samples of high levels of clonal heterogeneity as a favorable prognostic factor in HHD‐B‐ALL.

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