Barely Significant
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Heterogeneity of Circulating Tumor Cell-Associated Genomic Gains in Breast Cancer and Its Association with the Host Immune Response.

Cancer Res · 2021 · PMC9397625 · PMID 34711609

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a clear trendno p-value reported
In metastatic breast cancer, there was a clear trend for selection of cells with CTC gains, starting from lower frequency clones in primary tumors to almost completely making up the metastatic tumors.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.