showed a trendp = 0.037
The ANOVA for ESR1 test showed a significant difference between age/sex groups (F 5,23 = 2.882; p = 0.036) while the post hoc Tukey tests only showed a trend of slightly higher expression in the oldest males compared to the youngest males (adjusted p = 0.037; Figure 2 ) while its expression was comparable among other comparisons (adjusted p > 0.128; Figure 2 ).