Antitumor Activity of the Novel BTK Inhibitor TG-1701 Is Associated with Disruption of Ikaros Signaling in Patients with B-cell Non-Hodgkin Lymphoma.

Clin Cancer Res · 2021 · PMC9401565 · PMID 34551904

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a clear trendno p-value reported

S3B), a clear trend in the upregulation of Ikaros-repressed genes and downregulation of Ikaros-enhanced genes was seen in TG-1701 early-responsive patients only ( Fig. 3B ).

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