Leber Hereditary Optic Neuropathy: Molecular Pathophysiology and Updates on Gene Therapy.

Biomedicines · 2022 · PMC9405679 · PMID 36009477

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did not reach statistical significanceno p-value reported

A clinical trial of idebenone showed that the secondary endpoint of change in best-corrected visual acuity was significantly better with Raxone use, while the primary endpoint of best recovery in visual acuity did not reach statistical significance [ 28 ].

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