[ 15 ], a slight trend towards a better five-year DFS for S-1 was observed (HR =1.05, 95% CI 0.88–1.26).
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Efficacy of S-1 or Capecitabine Plus Oxaliplatin Adjuvant Chemotherapy for Stage II or III Gastric Cancer after Curative Gastrectomy: A Systematic Review and Meta-Analysis.
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[ 16 ], S-1 chemotherapy showed a trend toward a better five-year DFS in stage II (HR 1.85, 95% CI 0.69–4.92); however, there was no difference in the five-year DFS between the two regimens in stage III (HR 0.94, 95% CI 0.66–1.34).