Long-Term Evaluation of Gastroesophageal Reflux in Neonates with and without Preventive Anti-reflux Surgery at the Time of Congenital Diaphragmatic Hernia Repair.

Patients with patch repair of the diaphragmatic defect also had considerably more moderate or severe GER symptoms than patients whose diaphragmatic defect was repaired primarily, but this did not quite reach significance ( p = 0.051).

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An almost significant difference was found between the two groups at the age of six months and none during the further follow-up of two years.

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In patients who required secondary anti-reflux surgery, a higher rate of primary fundoplication was noted, but this difference did not quite reach statistical significance. 3.4.

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In patients with preventive fundoplication, the rate of secondary anti-reflux surgery during follow-up was even higher although it did not reach statistical significance.

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When dividing the cohort into patients with small and large defects, a highly significant difference could be detected revealing a markedly lower body weight for children with large CDH in all age groups.

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