The Role of Soy Isoflavones in the Prevention of Bone Loss in Postmenopausal Women: A Systematic Review with Meta-Analysis of Randomized Controlled Trials.

J Clin Med · 2022 · PMC9409780 · PMID 36012916

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moderately significantp < 0.000not a probability at all

[ 45 ], in the meta-analysis based on 26 RCTs (2652 women), showed a moderately significant effect of isoflavones on bone loss in estrogen-deficient women (WMD (g/cm 2 ) in LS 0.01 (95% CI: 0.01, 0.02), p < 0.000 and in TH 0.001 (95%: CI 0.00, 0.02), p < 0.01).

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