Enhanced Feedback Inhibition Due to Increased Recruitment of Somatostatin-Expressing Interneurons and Enhanced Cortical Recurrent Excitation in a Genetic Mouse Model of Migraine.

The peak amplitude of the disynaptic inhibitory current was reached earlier along the train (at the seventh AP, after which it tended to decline) and was (85%) larger in FHM1 compared with WT mice (18.5 ± 6.5 pA, n = 5, t (10) = 1.46, p = 0.17 t test), but the difference did not reach statistical significance, because of the large variability ( Fig. 4 B , C ).

also in 111,027 other papers