Role of genetics in amyotrophic lateral sclerosis: a large cohort study in Chinese mainland population.

J Med Genet · 2022 · PMC9411893 · PMID 34544842

Europe PMC DOI

hedged sentence

0.0080

closest p · 0.2× alpha

0.0080

boldest claim

The sentences

approached significancep=0.008actually significant

Interestingly, rare P/LP variants in two genes, TBK1 and NEK1 , identified as ALS causative genes by whole-exome analyses and gene burden analyses, 12 13 were also enriched in ALS from our cohort, and the p value approached significance (p=0.008 and p=0.002, respectively).

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