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Clinical Utility of the Sivelestat for the Treatment of ALI/ARDS: Moving on in the Controversy?

Intensive Care Res · 2023 · PMC9412801 · PMID 36911225

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a negative trendno p-value reported
Although prespecified stopping guidelines were not met, a negative trend in long-term mortality prompted the DSMB to recommend suspension of enrollment and discontinuation of study drug [ 9 ].

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