21st ISoP Annual Meeting “A New Era of Pharmacovigilance: Challenges and Opportunities” 20–23 September 2022 Verona, Italy

Drug Saf · 2022 · PMC9421640

Europe PMC

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highly significantno p-value reported

Due to the large number of spontaneous reports associated to covid-19 vaccines, highly significant TTO signals could be detected whereas there are no clinically relevant unexpected temporal patterns.

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a significant trendno p-value reported

In BIFAP, there was a significant trend increase after 2018 RMMs in the utilization of contraceptives before the initiation of an oral retinoid treatment, but still far below 100% (15% maximum).

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an increasing trendno p-value reported

lano, Italy; 14 Biogen Idec Italia, Pharmacovigilance, Milano, Italy Introduction: Digital media are integrated in our daily routine, play a critical role in the dissemination of health information and disease prevention guidelines and are becoming more impacting in pharmacompanies activities, with an increasing trend after the pandemic period.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.