Management of medication overuse (MO) and medication overuse headache (MOH) S1 guideline.

Neurol Res Pract · 2022 · PMC9422154 · PMID 36031642

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did not reach statistical significanceno p-value reported

The number of days with acute medication use was also reduced in the topiramate group, although the difference from the placebo group did not reach statistical significance [ 40 ].

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