Huntington's disease phenotypes are improved via mTORC1 modulation by small molecule therapy.

PLoS One · 2022 · PMC9423655 · PMID 36037192

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a strong trendno p-value reported

Under cardiac stress, NV-5297-treated HD mice experienced an increased pS6/S6 ratio in the striatum and a strong trend toward increased ratios in the heart ( Fig 8A and 8B ).

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