Effect of Baloxavir and Oseltamivir in Combination on Infection with Influenza Viruses with PA/I38T or PA/E23K Substitutions in the Ferret Model.

mBio · 2022 · PMC9426601 · PMID 35938724

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did not reach statistical significanceno p-value reported

Viral shedding in ferrets treated with the combination of oseltamivir and baloxavir gave an average reduction of 34% (AUC = 16.8 ± 3.4, P = 0.064) relative to placebo (AUC = 25.1 ± 2.9), but the difference did not reach statistical significance ( Fig. 4a ).

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