Glucocorticoids' treatment impairs the medium-term immunogenic response to SARS-CoV-2 mRNA vaccines in Systemic Lupus Erythematosus patients.

Sci Rep · 2022 · PMC9427088 · PMID 36042275

Europe PMC DOI

hedged sentence

0.3136

closest p · 6.3× alpha

0.3136

boldest claim

The sentences

did not reach statistical significancep = 0.3136not close (p > 0.1)

As a result, declines in nAB titres were of a substantially higher magnitude in patients treated with Glucocorticoids than those observed in non-users (First-Line: 85%, p = 0.0022; Third-Line: 87%, p = 0.0015), where differences did not reach statistical significance (First-Line: 39%, p = 0.3136; Third-Line: 46%, p = 0.2246).

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