PI3K signaling specifies proximal-distal fate by driving a developmental gene regulatory network in SOX9+ mouse lung progenitors.

Elife · 2022 · PMC9427112 · PMID 35976093

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did not reach statistical significanceno p-value reported

A significant increase in the number of Sox9+ epithelial cells was only observed at E18.5; in fact, the mean proportion of epithelium expressing Sox9 at E12.5 and E14.5 was slightly lower in Pik3ca cKO embryos (although this did not reach statistical significance).

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