A toolbox for class I HDACs reveals isoform specific roles in gene regulation and protein acetylation.

PLoS Genet · 2022 · PMC9436093 · PMID 35994477

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showed a trendno p-value reported

Cells expressing HDAC1 CI in both wildtype or KO background showed a trend towards lower cellular activity, while expression of HDAC2 CI led to a significant reduction of total cellular histone deacetylase activity ( Fig 2B ).

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