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An ACE2-IgG4 Fc Fusion Protein Demonstrates Strong Binding to All Tested SARS-CoV-2 Variants and Reduced Lung Inflammation in Animal Models of SARS-CoV-2 and Influenza.

Pathog Immun · 2022 · PMC9438944 · PMID 36072571

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Weight differences between treatment groups did not reach statistical significance due to significant inter-animal variation and small group size.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.