Assessing the Emergence of Resistance in vitro and Invivo: Linezolid Combined with Fosfomycin Against Fosfomycin-Sensitive and Resistant <i>Enterococcus</i>.

Infect Drug Resist · 2022 · PMC9440711 · PMID 36065277

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a decreasing trendno p-value reported

a slightly increasing trendno p-value reported

24 Subsequently, RT-qPCR revealed that the overall virulence factor of the mutant decreased, with cylA and esp showing a decreasing trend on average, while asaL showed a slightly increasing trend at NO.24.

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showed a trendno p-value reported

However, Yan et al showed a trend of gradual drug resistance when a sub-inhibitory concentration of 1 mg/L linezolid was used in the treatment of VRE. 11 According to a survey of 1442 clinically collected Enterococcus isolates in the Czech Republic from 2009 to 2019, linezolid-resistant Enterococcus faecalis (LREF) increased from 0

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