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Lumican is elevated in the lung in human and experimental acute respiratory distress syndrome and promotes early fibrotic responses to lung injury.

J Transl Med · 2022 · PMC9440861 · PMID 36059026

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showed a trendno p-value reported
It showed a trend of declining levels of BALF TNF-α and fibronectin from day 1 to day 7 while the lumican and COL3A1 levels remained relatively stable.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.