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Oncogenic fusion of BCAR4 activates EGFR signaling and is sensitive to dual inhibition of EGFR/HER2.

Front Mol Biosci · 2022 · PMC9445485 · PMID 36081848

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Liver metastasis caused by the CD63-BCAR4 fusion gene was also reduced in canertinib-treated mice, although the difference did not reach statistical significance ( Figure 5B ).

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