Immune effector cell associated neurotoxicity syndrome in chimeric antigen receptor-T cell therapy.

Front Immunol · 2022 · PMC9445841 · PMID 36081506

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did not reach statistical significanceno p-value reported

T cells and macrophages were observed in the brains of mice with neurotoxicity and a decrease in raw averages was observed in mice treated with GM-CSF neutralizing antibodies (although it did not reach statistical significance) ( 44 , 48 ).

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