Administration of vitamin D and its metabolites in critically ill adult patients: an updated systematic review with meta-analysis of randomized controlled trials.

A p value < 0.05 was considered significant and values > 0.05 but < 0.20 were considered a trend towards significance (for hypothesis-generating purpose).

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In addition, overall and 28-day mortality showed a trend towards reduced mortality in the vitamin D deficient group after supplementation compared to placebo.

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